- Description
- Data sheet
SR-9011
SR-9011 is a research drug developed by Professor Thomas Burris of the Scripps Research Institute. It acts as an agonist for Rev-ErbAα and has a half-maximal inhibitory concentration (IC50) of 790 nM for Rev-Erbα and an IC50 of 560 nM for Rev-ErbAβ. This medicine is mainly used for research into the regulation of the circadian rhythm and its possible implications for the immune system, inflammatory processes and cancer.
SR-9011 belongs to the second generation of Rev-ErbA activators and is present in high concentrations in various tissues such as the liver, skeletal muscle, adipose tissue and brain.
For more information, see the study on SR-9009 and SR-9011
CONCENTRATION
20 mg / ml.
DISCLAIMER
This material is sold for use in laboratory research only. Terms of sale apply. Not for human consumption, nor for medical, veterinary or household use. Familiarize yourself with our DISCLAIMER before ordering.
Application |
Rev-ErbA-agonist |
CAS |
1379686-29-9 |
molar massa |
479.04 g/mol |
Chemical formula |
C 23 H 31 ClN 4 O 3 S |
IUPAC name |
3-[[(4-chlorophenyl)methyl-[(5-nitrothiophen-2-yl)methyl]amino]methyl]-N-pentylpyrrolidin-1-carboxamide |
Synonyms |
SR9011, 1379686-29-9, SR-9011, CHEMBL1961797, GTPL8900, MolPort-044-561-120, PPUYOYQTTWJTIU-UHFFFAOYSA-N, KS-00000TT2, BDBM50366239, AKOS030526466, CS-89,61 SR 8-6, 5 SR-4668, HY , 1-pyrrolidinecarboxamide, 3-((((4-chlorophenyl)methyl)((5-nitro-2-thienyl)methyl)amino)methyl)-n-pentyl-, 3-[[(4-chlorophenyl)methyl- [(5-nitrothiophen-2-yl)methyl]amino]methyl]-N-pentylpyrrolidine-1-carboxamide |
Bulletin |
Store at room temperature, tightly closed, away from heat, light and moisture. |
Solubility |
Soluble in DMSO, Ethanol. Slow degradation in PEG400, PPG |
Organoleptic profile |
Clear liquid |
Physical form |
Solution in PPG and DMSO |
Specification |
20mg/mL ±5% |
Terms and conditions |
This material is sold for use in laboratory research only. Terms of sale apply. Not for human consumption, nor for medical, veterinary or household use. Please familiarize yourself with our DISCLAIMER before ordering. |
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