
OTR-AC (MK-29, OSTARINE-O-ACETATE)
Wat is OTR-AC?
OTR-AC, also known as MK-2866 Ester, is MK-2866 (Ostarine) that has undergone esterification (the process of combining an organic acid with an alcohol). This chemical process is used to maximize potency and extend the half-life (the time required for a quantity to reduce to half of its original value) of a substance. As a result of this process, the ester version of ostarine has the capacity to remain bioactive ten times longer. This results in benefits such as reduced dosing frequency and more stable blood levels.
Operation
As the ester version of the selective androgen receptor modulator (SARM) ostarine, OTR-AC is more powerful and has longer-lasting effects. By binding to proteins in the body known as androgen receptors, it stimulates the formation of muscle tissue. This, in turn, leads to an increase in muscle mass and strength.
Research on OTR-AC
Increase in muscle mass and strength
Studies suggest that OTR-AC, along with other SARMs, increases muscle mass and strength by stimulating the formation of muscle tissue:
- In adult rats, the administration of SARMs, including OTR-AC, resulted in an increase in lean muscle mass and a decrease in body fat percentage.
- In older male and female rats, the administration of OTR-AC resulted in an increase in lean muscle mass, a decrease in fat mass, and significant improvements in their ability to climb stairs.
- Studies have shown that OTR-AC can help increase muscle mass in rats with cancer cachexia (muscle loss).
- In older male and female rats, OTR-AC significantly improved total lean body mass and physical function.
- In rats from which the ovaries had been surgically removed, OTR-AC improved the muscle tissue.
- In rats, increased OTR-AC raised muscle mass by increasing the production of muscle cells.
Reduction of body fat
"In addition to helping gain muscle mass, it has been shown that OTR-AC also reduces total body fat:"
- In phase I and II clinical trials, OTR-AC has shown promising results in increasing total lean body mass, reducing total tissue fat percentage, and improving functional performance.
- An overview of studies showed that OTR-AC can help increase lean body mass and reduce body fat in overweight rats.
- In a phase 2a study, the administration of OTR-AC together with other SARMs resulted in an increase in lean fat mass and a decrease in body fat percentage.
- In male rats, OTR-AC increased the breakdown of fat cells by improving fat metabolism and influencing the release of adiponectin (a hormone that regulates the breakdown of fatty acids).
Improvement of bone health
Studies suggest that OTR-AC may help stimulate bone formation and protect against bone diseases:
- In rats from which the ovaries had been surgically removed, the administration of OTR-AC resulted in improved bone healing.
- In a rat model for age-related osteoporosis in male rats, both OTR-AC and testosterone treatments improved bone healing by increasing callus volume and surface area, bone volume and density, and bone width.
- In a rat model of postmenopausal osteoporosis, high doses of OTR-AC over 5 weeks resulted in an increase in bone volume, density, and bone mineral density.
Lowering of cholesterol levels
Evidence suggests that OTR-AC may help lower cholesterol levels, particularly low-density lipoprotein (bad cholesterol):
- In older male and female rats, the administration of OTR-AC resulted in a significant reduction in low-density lipoprotein levels.
- In rats whose ovaries had been surgically removed, treatment with OTR-AC reduced blood levels of cholesterol.
🧪 Contents
The jar contains 1 gram of pure OTR-AC powder.
A measuring scoop is not included.
'For accurate weighing, we recommend using a precision scale.'
📄 Disclaimer
This material is sold exclusively for use in laboratory research. Sales conditions apply. Not for human consumption, nor for medical, veterinary, or household use. Familiarize yourself with our DISCLAIMER before ordering.
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