OTR-AC (MK-29, OSTARINE-O-ACETATE)

What is OTR-AC?

OTR-AC, also known as MK-2866 Ester, is MK-2866 (Ostarine) that has undergone esterification (the process of combining an organic acid with an alcohol). This chemical process is used to maximize potency and extend the half-life (the time required to reduce an amount to half of its original value) of a substance. Through this process, the ester version of ostarine has the capacity to remain bioactive ten times longer. This results in benefits such as reduced dosing frequency and more stable blood levels.

Mechanism

As the ester version of the selective androgen receptor modulator (SARM) ostarine, OTR-AC is more potent and has longer-lasting effects. By binding to proteins in the body known as androgen receptors, it stimulates the formation of muscle tissue. This in turn leads to an increase in muscle mass and strength.

Research on OTR-AC

Increase in muscle mass and strength

• In adult rats, administration of SARMs, including OTR-AC, resulted in an increase in lean muscle mass and a decrease in body fat percentage.
• In older male and female rats, administration of OTR-AC resulted in an increase in lean muscle mass, decrease in fat mass, and significant improvements in their ability to climb stairs.
• Studies showed that OTR-AC can help increase muscle mass in rats with cancer cachexia (muscle loss).
• In older male and female rats, OTR-AC significantly improved total lean body mass and physical function.
• In rats whose ovaries were surgically removed, OTR-AC improved muscle tissue.
• In rats, OTR-AC increased muscle mass by boosting the production of muscle cells.

Reduction of body fat

• In phase I and II clinical trials, OTR-AC has shown promising results in increasing total lean body mass, reducing total tissue fat percentage, and improving functional performance.
• A review of studies showed that OTR-AC can help increase lean body mass and reduce body fat in overweight rats.
• In a phase 2a study, administration of OTR-AC together with other SARMs resulted in an increase in lean body mass and a decrease in body fat percentage.
• In male rats, OTR-AC increased the breakdown of fat cells by improving fat metabolism and influencing the release of adiponectin (a hormone that regulates the breakdown of fatty acids).

Improvement of bone health

• In rats whose ovaries were surgically removed, administration of OTR-AC resulted in improved bone healing.
• In a rat model of age-related osteoporosis in male rats, both OTR-AC and testosterone treatments improved bone healing by increasing callus volume and surface area, bone volume and density, and bone width.
• In a rat model of postmenopausal osteoporosis, high doses of OTR-AC for 5 weeks resulted in an increase in bone volume, density, and bone mineral density.

Reduction of cholesterol levels

• In older male and female rats, administration of OTR-AC resulted in a significant reduction in low-density lipoprotein levels.
• In rats whose ovaries were surgically removed, treatment with OTR-AC reduced blood cholesterol levels.

🧪 Contents

This product contains 30 ml of liquid OTR-AC with a concentration of 25 mg/ml.
There is a glass pipette in the bottle with a scale from 0.2 ml to 1 ml, allowing you to dose easily and accurately.

📄 Disclaimer

This material is sold exclusively for use in laboratory research. Terms of sale apply. Not for human consumption, nor for medical, veterinary, or household use. Please familiarize yourself with our DISCLAIMER before ordering.