COLURACETAM

Coluracetam is a new and unique member of the racetam class of synthetic nootropics. Coluracetam, or N-(2,3-Dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxo-1-pyrrolidinyl)acetamide, is a synthetic compound of the racetam family. Racetams share a pyrrolidine core, a five-membered nitrogen-containing ring with a ketone-bonded oxygen at R2. This 2-pyrrolidone ring is bonded to the terminal carbon atom of an acetamide group, an ethylamide chain with a ketone bond (C=O) at the alpha carbon atom.

Originally developed as a potential treatment for Alzheimer's disease and later considered a treatment for depression and anxiety, coluracetam has become a popular nootropic known for elevating mood, increasing motivation and enhancing the eyesight. Coluracetam was first synthesized in 2005 by Japan's Mitsubishi Tanabe Pharma Corporation as a treatment for Alzheimer's disease. Coluracetam is a nootropic derived from racetam, although very different from other compounds such as Piracetam and Aniracetam. Coluracetam appears to interact with a process known as high-affinity choline uptake, which is the rate-limiting step of drawing choline into a neuron for synthesis into the neurotransmitter acetylcholine.

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